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Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1
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High-dose iron: May reduce antioxidant effectiveness when not medically needed
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For those with sleep disorders, melatonin levels are lower which can also affect overall daily functioning
