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If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every 3 to 4 days for another 2 to 3 weeks

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Published data shows AOD-9604 has measurable oral bioavailability estimated at 3-10% in animal models unusual for a 16-amino-acid peptide, since most peptides of this size are completely degraded by gastrointestinal proteases

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