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Another binding protein with ligand-independent activity is IGFBP-4, which physically interacts with Frz8, a Wnt receptor, in cardiomyocytes and inhibits activation by Wnt3A ligand [77]

Bueno, M., Calyeca, J., Rojas, M

Peptide Therapy While IGF-1 is frequently prescribed, peptide therapy is also effective

10.3390/nu15040889 110

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