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Anxiety-like behavior can be induced in rats through intracerebroventricular streptozotocin (ICV-STZ) injections, which is accompanied by diffuse amyloid plaques in the hippocampus, enlargement of ventricles, and spine loss in the dentate gyrus (Roy et al., 2022)

Mechanistically, SAT1 did not affect the expression or activity of SLC7A11 and GPX4

10.1002/anie.202300379 234 ZengT.LiJ.XieL.DongZ.ChenQ.HuangS.et al (2023b)

Its part of a class of treatments known as "lipotropic" injections, which help break down fat in the body more efficiently

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However, as individuals age many biological processes deteriorate resulting in impaired function and disease