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Peptide lists with calculated ratios were then processed through an in-house Python script that first annotated the cysteine residues and then calculated a median value of peptides containing the same cysteine residue

doi: 10.1371/journal.pone.0042935

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In contrast, the non-amyloidogenic pathway is characterized by more active -secretase-catalyzed cleavage (e.g., ADAM-10 and ADAM-17) of APP, releasing soluble APP from neuronal membranes into the interstitial space of the brain

Authoratative review concerning potential involvement of kynurenic acid abnormalities in schizophrenia