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The reduction in the potential of the mitochondrial membrane due to disturbances in energy metabolism can significantly impact cellular functions

This made unfeasible to routinely check PTTG2 protein levels during the study

doi: 10.1186/S12937-025-01193-7 119

NF-B in biology and targeted therapy: New insights and translational implications

Methylation is considered a key process in the synthesis of glutathione because part of the methylation cycle directly contributes to the production of cysteine, an essential amino acid needed to build glutathione molecules

Transcriptomic analysis was used to examine the potential mechanisms, followed by both in vitro and in vivo validation of key protein expression levels in the ACSL4/ALOX15 signaling pathway