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An open-label study in patients with episodic migraine ( n = 25) assessed a PEA-containing nutraceutical (Calmux, Bioksan, Spain

10.1177/08968608211008095 40 MasolaV.BonominiM.OnistoM.FerraroP

A trend of increasing prevalence of AIH has been observed worldwide, along with a relative increase in the percentage of male patients

Interestingly, mediation analysis showed that TMAOs adverse effect on kidney function strengthened at more severe stages of cardiometabolic disease, implying TMAO synergy with existing pathology (thereby providing 2-hit model)

J Nutr Environ Med
