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Indeed, humans with homozygous loss-of-function mutations in the ANGPTL3 gene have low serum levels of not only triglycerides and apo-B-containing lipoproteins (VLDL/LDL) but also low levels of apoA-I lipoproteins (HDL)

Subsequently, the protein was found to be expressed at various levels in the liver, intestine, umbilical cord, placenta, sweat gland, human brain endothelium, and more recently as a differentiation marker on chondrocytes and osteoblasts [7, 30]

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So, what lipids should you measure and how often should you repeat them