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While berberine is safe for most people to use, there are some possible side effects, like abdominal discomfort, constipation, diarrhea and nausea

doi:10.1016/j.mcna.2022.10.004

During in vitro fertilization (IVF) embryo transfer, vitamin C supplementation is provided to the patients during hormonal stimulation to ensure higher concentration of vitamin C in the follicular fluid [94]

Indole acts as a nucleophile to displace a water molecule and the elimination-addition ends by indole condensing with a 3-carbon unit to form tryptophan