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Oral administration of CDK4/6 inhibitor palbociclib can induce prolonged G1 cell cycle arrest

Psychoneuroendocrinology 47, 19

This notion was confirmed using metabolic cages, revealing that GLP-1MK-801 counteracted the decrease in energy expenditure that is engaged by calorie-restricted mammals as an adaptive starvation response to protect the organism from an excessive loss of body weight and fat mass (Fig

Tumor heterogeneity leads to markedly divergent ERS-death axis characteristics (e.g., differential responses between ER and triple-negative breast cancers) [15, 16, 26], complicating the establishment of unified treatment protocols

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