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PPAR and 15-PGDH were induced, the activity of NF-B (p65 ser536 /NF-B) was suppressed, mTOR signaling was inhibited (pP70S6K Thr389/P7056 ), and PI3K signaling was reduced (pAKt ser473/ AKt)

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The HGF gene is mapped on the long arm of chromosome 7 of q21.1, and alternative splicing results in multiple transcripts, at least one of which encodes an inactive pre-pro-HGF

In the other experiments using the same surgical procedure and the same site of the nerve, a crush injury with microsurgical forceps was induced for 60 seconds and NaBPC157 was applied locally

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