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Some aspects, including DNA methylation and histone modification, have been recently described by Sharma et al
doi: 10.1200/CCI.18.00069

Liu SZ, He XM, Zhang X, Zeng FC, Wang F, Zhou XY

Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis in rats: possible role of SIRT1/Nrf2/HO-1 pathway

Brain inflammation is also recognized as a contributing mechanism in epilepsy [329]

In another study, rats with diabetic kidney disease (DKD) were treated with a CD38 inhibitor, resulting in increased renal NAD + levels, which in turn decreased mitochondrial oxidative stress 144
