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Although it does not appear to interact with the gut microbiota directly, evidence suggests that the vagus nerve can sense microbial signals in the form of bacterial metabolites, or be influenced via microbiota-mediated modulation of enteroendocrine (EECs) and enterochromaffin (ECCs) cells in the gut epithelium 86 (Figure 2)
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Its levels fall with age, so a supervised plan can help rebuild firmness and reduce shedding gradually
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