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doi: 10.1007/s12011-019-1654-5 94
They are generated by external sources such as UV radiation, smoke, stress, environmental pollution and poor nutrition
doi: 10.1016/j.smim.2019.04.003 232 HinojosaCAAkula Suresh BabuRRahmanMMFernandesGBoydAROrihuelaCJ
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this seems to be associated with increased level of inflammatory response
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