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Obviously, as indicated (Sikiric et al., 2018), there is an inescapable diversity of the carriers and thereby, an evident diversity of the obtained beneficial effects, and disable conclusion

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The epithelial tight junction proteins, the most apical component of epithelial intracellular junctions, equip IECs with this function, which seals the paracellular space between the cells and tightly restricts the transport of hydrophilic molecules 22,23,24