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These observations have prompted growing interest in non-hormonal contributors to hypothyroidism, particularly the role of the gut microbiota
In rice, WRKY45 is a positive regulator of resistance against the hemibiotrophic rice blast fungus Magnaporthe grisea

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In addition, erastin directly inhibits the activity of system x c - , resulting in the reduction in GSH production and inhibition of GPX4 activity, leading to accelerated production of ROS and ferroptosis ( in vivo
