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Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes

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Associated full thickness tearing of the insertion of the medial patellofemoral ligament complex (green arrow)

KEGG pathway enrichment analysis revealed that AMPs primarily modulated pathways involved in amino acid metabolism, including arginine and proline metabolism, alanine, aspartate and glutamate metabolism, glycine, serine and threonine metabolism, and histidine metabolism, as well as steroid hormone biosynthesis, riboflavin metabolism, glycolysis/gluconeogenesis, and arachidonic acid metabolism at T2 (Figure 8a)
