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Genetic studies were assessed for quality using the Newcastle Ottawa Scale plus additional criteria that included consideration of Hardy Weinberg equilibrium, power of the study, population stratification and correction for multiple comparisons
N-acetyl cysteine (NAC) is the current standard of care for APAP overdose 12 , which is It is believed to have benefit in APAP hepatotoxicity by increasing the availability of the glutathione precursor cysteine, thereby driving glutathione synthesis

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doi: 10.1111/j.1365-3040.2011.02400.x 57 PadmanabhanM

But there are not direct researches to study the benefits of free amino acids in BPD

Figure 1 GSH1 (EC 6.3.2.2) is exclusively present in plastids, while GSH2 (EC 6.3.2.2) has dual localization in plastids and the cytosol, both encoded by a single gene (Wachter et al., 2005)
