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Cerminati S, Eberhardt F, Elena CE, Peir S, Castelli ME, Menzella HG

Reduced levels of SIRT3 have been associated with OS and mitochondrial damage [75]

In summary, the nature of melanocytic lesions is a reflection of the remarkably nomadic embryologic process undergone by neural crest cells and melanoblasts, with participation of a specific molecular milieu, expression of metalloproteinases, EMT, and cell adhesion changes and dissemination using preexisting structures, all of which tend to be recapitulated in malignant melanocytic lesions (26)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Scofield M.D., Heinsbroek J.A., Gipson C.D., Kupchik Y.M., Spencer S., Smith A.C.W., Roberts-Wolfe D., Kalivas P.W