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In males, oxidative stress has been implicated in sperm dysfunction and damage caused by ROS

Indeed, in a mouse model of Mg2+ deficiency, immunochemistry revealed that substance P is increased by 230 and 200% in megakaryocytes and lymphocytes, respectively, after 1 day of Mg2+ depletion [46]

Interestingly, a significant linear correlation was found between the intensity changes observed for spot B and the changes in serum IGF-1 levels (Fig

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Min T, Bain SC

& Baird, B
