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We have found a very good concordance between both assays for patients that are monoinfected with a single genotype

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References 1.Lei D, Yu W, Liu Y, Jiang Y, Li X, Lv J

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Based on these findings we established that applying a semiquantitative fundus spot scale as a screening tool to our forward genetics pipeline, and using continuous variable phenotype data for linkage analysis, is an effective approach to identify genetic mutations associated to both the accumulation of fundus spots and the development of retinal degeneration

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