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Keywords: Alzheimers Disease, GHK-Cu, 5xFAD transgenic mouse, Intranasal administration, Amyloid plaques, Neuroinflammation Introduction Alzheimers disease (AD) is a complex disease and efforts to find effective treatments have met with limited success in part because the focus has been on testing drugs that target a specific pathogenic mechanism

The mechanism that is involved in hepatoprotective effect of coffee is unclear yet and future prospects may be considered

Glutamate is a pivotal metabolite in both cellular metabolism and brain function

stable for up to 24 months [16]

Banerjee A, Dubnau E, Quemard A, Balasubramanian V, Um KS, Wilson T, et al

In 2000 he moved to Bellinzona, where he helped open the IRB and directed the Signal Transduction Laboratory