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Patients with clinically occult regional nodal metastases may benefit from ultrasound surveillance of regional lymph nodes and adjuvant therapy.[9-14] Evidence (SLNB versus observation): The International Multicenter Selective Lymphadenectomy Trial (MSLT-1) included 1,269 patients with intermediate-thickness (defined as 1.23.5 mm in this study) primary melanomas

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This approach reflects how providers manage PT-141 dosing in clinical settings