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The increased lactate levels due to increased glycolytic flux in HNSCC has shown to potentially suppress the proliferation activity of human CTLs [107]
During internalization, the overexpressed intracellular HA enzymes in tumor cells would decompose the nanoparticles, releasing their contents
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doi: 10.3109/00498258809042225
Cannon JR, Greenamyre JT (2013) Gene-environment interactions in Parkinsons disease: specific evidence in humans and mammalian models
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