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Pro-inflammatory mediators such as cytokines induce the expression of inducible nitric oxide synthase (iNOS) and increased NO production can combine with ROS to form peroxynitrate, which is a potent inhibitor of mitochondrial respiration and energy production (Nesci et al., 2021)
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The intentional use of mercury in skin-lightening cosmetics is prohibited by the Drugs and Cosmetics Act 59
Lifestyle factors and age can influence longevity
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Forsyth et al., 1993) and methemoglobinemia in pediatrics (Geller et al., 2006)
