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J Pharmacol Sci 95: 1926

[DOI] [PubMed] [Google Scholar] 27.Liu Z., Huang J., Kang D., Zhou Y., Du L., Qu Q., Wang J., Wen L., Fu D., Hu Z., et al

Influence of PARP-1 inhibition in the cardiotoxicity of the topoisomerase 2 inhibitors doxorubicin and mitoxantrone

This results in a decrease in mitochondrial transcription factor TFAM and impaired mitochondrial function, which ultimately leads to increased vulnerability to oxidative stress and neuronal deterioration (Sharma A

Most patients actually find it relaxingmany fall asleep during treatment

Depending on the study design, DSIP may serve as a comparator or probe for investigating how specific peptide signals relate to circadian patterns, stress responses, and downstream molecular readouts