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doi: 10.3389/fphar.2018.01082 60 ChaconMRLozano-BartolomeJPortero-OtinMRodriguezMMXifraGPuigJet al
Primary bile acids (BAs) derived by Cholesterol are regulated by the nuclear FXR and the TGR5 and convert into secondary bile acids through 7-dehydroxylation reaction, which includes deoxycholic acid and lithocholic acid [194, 195]
These results indicate that these data are reliable and can be used for subsequent analyses
Esto le permite proteger las clulas nerviosas, mejorar la memoria y la concentracin mental , y tambin se utiliza a menudo para combatir la fatiga mental y el estrs oxidativo
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By identifying a core set of 62 cross-validated mitochondrial genes and establishing high-confidence metabolite-gene correlations (notably MTHFR-homocysteine and PDHA1-acetyl-CoA), the authors demonstrate significant sex-dimorphic flux alterations within the tricarboxylic acid (TCA) cycle and mitochondrial transport subsystems, particularly pronounced in females
