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Jacquinet, E., Rao, N

Epidemiological data reveal an increasing global burden, presently impacting over 350 million individuals, with World Health Organization forecasts indicating that MDD will emerge as the foremost cause of disability worldwide by 2030 [4,5]

G.LocatelliG.KingN

10.1038/nn.2682 [DOI] [PMC free article] [PubMed] [Google Scholar] Cashman NR, Durham HD, Blusztajn JK, Oda K, Tabira T, Shaw IT, Dahrouge S, & Antel JP (1992)

[DOI] [PubMed] [Google Scholar] 175.Vaarala O

Collectively, these observations highlight myelin degeneration as an early event and significant pathological feature in AD progression, which may contribute to disease-related cognitive decline