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[DOI] [PMC free article] [PubMed] [Google Scholar] Odamaki, T

Life Sci 87:139146 Ferreira GC, Tonin A, Schuck PF, Viegas CM, Ceolato PC, Latini A, Perry ML, Wyse AT, Dutra-Filho CS, Wannmacher CM, Vargas CR, Wajner M (2007) Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism

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Caffeine increases neurotransmitter release by abolishing the inhibitory control of acetylcholine in the hippocampus and prefrontal cortex

This is partly because ALCAR is partially hydrolyzed (broken down into standard L-carnitine) by enterocytes in the intestines during the absorption process

Consequently, targeted educational initiatives and improved access to qualified healthcare services may play a critical role in effective prevention and harm-reduction strategies (46, 47)