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Tesamorelin has approval for HIV-associated lipodystrophy

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doi:10.1016/s0301-0082(99)00008-8 Orr JE, Malhotra A, Sands SA

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However, excessive ammonia accumulation induces a novel form of cell death in effector T cells, termed Ammonia death ( Distinct from traditional cell death mechanisms such as apoptosis, necrosis, and pyroptosis, ammonia-induced cell death (termed Ammonia death) is a novel form of cell death triggered by overload of glutamine-derived ammonia, leading to the demise of effector T cells

Abubakar-Waziri, H
