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Apoptosis induced by vitamin D compounds in breast cancer cells is inhibited by Bcl-2 but does not involve known caspases or p53
Moreover, OPi, a novel OXPHOS complex I inhibitor, showed antitumor activity in MAPKi-resistant BRAF-mutant melanoma by promoting glycolytic metabolism and suppressing the TCA cycle through the LKB1-AMPK axis [55]
Glutathione works on skin pigment production by inhibiting tyrosinase, an enzyme involved in making melanin
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Huang CS, Moore WR, Meister A
