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They are primarily used as adjunct therapy to levodopa to reduce motor fluctuations, particularly the wearingoff phenomenon [3, 6]
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The central clock located in the suprachiasmatic nucleus of the anterior hypothalamus synchronizes the timekeeping in the peripheral tissues by integrating the light-dark input from the environment

Chit xut rau m : Ngn chn s hnh thnh ca hc sc t melanin, dng da trng sng, ngn nga tc hi t tia UV, chng vim, khng khun, lm mt v mn da, iu tit tuyn b nhn, gip hng thong ln da
In addition, integrative approachessuch as combining probiotics with digital healthsupported managementmay enhance broader outcomes, including nutritional status, systemic inflammation, and quality of life (Ou et al., 2021

Journal of Pediatric Gastroenterology and Nutrition 68(1): p 26-29, January 2019.
