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CBT is the most empirically supported approach, helping patients identify and modify maladaptive painrelated thoughts (catastrophizing), behaviors (avoidance), and emotional responses (fear, anxiety) to improve coping and function

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Summary Keywords allergic asthma, immunometabolism, innate immunity, innate lymphoid Cells (ILC2), pentose phosphate pathway, redox homeostasis and signaling, respiratory immunology Citation Cain J, Hurrell BP, Shen S, Speliakos P and Akbari O (2026) Melatonin suppresses ILC2-driven airway hyperreactivity via glutathione-dependent metabolic reprogramming

Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects