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The metabolomic approach to the gut microbiome suggests that the diminished SCFA level caused by the lower abundance of Firmicutes and similar bacteria may have an effect on the immune system

Acute and delayed effects of DSIP (delta sleep-inducing peptide) on human sleep behavior

Eur J Nucl Med Mol Imaging 39:17671777

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Wu X., Yu G., Parks H., et al., Circadian Mechanisms in Murine and human Bone Marrow Mesenchymal Stem Cells Following Dexamethasone Exposure, Bone 42, no

Thus, pharmacological strategies that aim to restore balance between IRE1s XBP1s and RIDD activities are not only limited to anticancer therapies but can also be crucial for effective treatments of metabolic disorders such as diabetes