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Description
Dyskinesia and motor fluctuations are other reported adverse events of levodopa after prolonged usage that can significantly impact the quality of life in the long term [14, 18]

Practical Considerations for Use Start Low, Adjust Gradually Begin with lower doses and increase based on research outcomes

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S2CID 11186195

That is the demand side

At the same time, they may need more of it because the body is dealing with more oxidative stress, more inflammation, and more disease pressure
