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The higher the percentage, the more intoxicated and impaired a person becomes

In fact, low B12 levels have been linked with poor antidepressant response (Alpert et al., 2003) and greater difficulty discontinuing SSRIs or SNRIs

Duration and timing: A limitation in the current evidence is the lack of long-term follow-up

Rats with thyroidectomy showed reduced absorption of oral vitamin B12, and the condition was reversed when the rats were supplemented with exogenous thyroid (Okuda and Chow, 1961)

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Importantly, these medications carry boxed warnings for medullary thyroid carcinoma risk and are contraindicated in patients with personal or family history of MEN2 or medullary thyroid carcinoma