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Physiological phases like lactation or pregnancy gave no statistically significant differences (Figure 1a) (Supplementary Table S3)

If a sulfur atom is bonded to sulfur atom of another cysteine, a covalent disulfide bridge is formed which is weaker (easier to split) than peptide bond, but stronger than any interaction of the other type (hydrogen bonds, salt bridges, hydrophobic and van der Waals interactions)

Open 4 (2), e2037341

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Overall, future research should prioritize the development of more targeted and comprehensive exosome-based therapeutic strategies
