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In 2016, ALOXs were investigated to oxidize polyunsaturated fatty acyl (PUFA) via phosphorylase kinase G2-dependent iron pools, leading to ferroptosis

J Crit Care 78:154396 Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL (2004) Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock

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Moreover, NK cells and Treg cells might also play important roles in platinum resistance of OC

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We also observed decreased GSH in BP compared to CON (CON, 1.7361.766