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The ALOX family can mediate PUFAs peroxidation to generate AA/AdA-PE-OOHs, thereby triggering ferroptosis (Lei et al., 2019)

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Programme grant support from Cancer Research UK (Professor Roland Wolf, C4639/A12330) is gratefully acknowledged

Oxidized Glutathione Glutathione exists in two states in the body: reduced glutathione, known as GSH, and oxidized glutathione, known as GSSG

Example B: Immunoglobulins The protein extinction coefficient () for most mammalian antibodies, known as immunoglobulins, typically falls within the range of 12 to 15

We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig