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GHRP-1 and ipamorelin are both GH secretagogues that target the ghrelin receptor in the pituitary gland to stimulate growth hormone synthesis
NNMT is overexpressed in white adipose tissue in obesity and insulin resistance
2025 Jun Amilia Ramadhani, Indwiani Astuti, Maria Goreti Widiastuti, Nunuk Purwanti

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While preclinical findings are encouraging, human clinical evidence remains limited , and the compound should be viewed as a research-stage metabolic therapy rather than an established treatment for obesity or weight management
