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Coenzyme Q10 and vitamin E deficiency in Friedreichs ataxia: predictor of efficacy of vitamin E and coenzyme Q10 therapy

Limited data available suggests that dose adjustment of Critizyme Tablet may not be needed in these patients

Also, genetic interactions between minor alleles in the selenoprotein S gene ( SELENOS ) and the nuclear factor erythroid 2-related factor 2 gene ( NFE2L2 ) increase chronic thyroiditis incidences (105)

These reasons can include a reduced intake of carnitine, or more commonly, an increased flow of carnitine out of the body via the kidneys