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Eur J Immunol 42: 32123222, 2012 [DOI] [PubMed] [Google Scholar] 188.Wan J, Forsyth AM, and Stone HA

A controlled trial that included 30 healthy volunteers with normal hearing found 600 mg lipoic acid daily for 10 days prior to experimental noise exposure reduced temporary noise-induced hearing loss better than a single 600 mg dose of lipoic acid one hour before noise exposure or no lipoic acid

Histamine is both produced and broken down in the gut

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Journal of Biological Chemistry 281, 1742017431 (2006)

A moderate increase in ROS levels can stimulate cell growth and proliferation, and allows for the normal physiological functions