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DI Pierro et al

J Coll Physicians Surg Pak

The initial LECs constitutively express CCL21 to actively recruit DCs via CCL21-CCR7 chemotaxis (105)

10.1111/resp.12984 Respirology 59 HtooA

This effect is partly mediated through the modulation of key cell cycle regulators such as cyclin D1 and p21, which facilitates progression from the G1 to S phase

Under oxidative damage conditions, Nrf2 transports to the nucleus, then binds to the antioxidant response element (ARE), and enhances sequence to initiate transcription of cytoprotective genes NF-E2 related factor 2 (Nrf2) has been seen to get modulated in various neurodegenerative diseases
