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As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

Lack of intrinsic factor typically leads to vitamin B12 deficiency

This proactive approach ensures you always have the perfect dose for your body

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However, no research directly compares continuous use versus cycling protocols (such as 12 weeks on, 4-8 weeks off), leaving optimal long-term strategies somewhat uncertain