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Finally, the use of L-carnitine (10-20 mg/kg body weight given as a slow bolus injection) is approved by the US FDA to treat L-carnitine deficiency in subjects with ESRD undergoing hemodialysis (76)

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Taylor EN, Stampfer MJ, Curhan GC

It has been found that the odds of developing any adverse events are highest for tricyclic antidepressants and serotonin noradrenaline reuptake inhibitors