how do glutathione serves as a reducing reagent in cells Glutathione-Related Enzymes and Proteins: Review Structure of glutathione The role

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Nrf2 controls the expression of key components of the glutathione (GSH) and thioredoxin (TXN) antioxidant system, as well as enzymes involved in NADPH regeneration, ROS and xenobiotic detoxification, heme metabolism, thus playing a fundamental role in maintaining the redox homeostasis of the cell

10.1038/nsmb.2754 [DOI] [PMC free article] [PubMed] [Google Scholar] Perrem K, Colgin LM, Neumann AA, Yeager TR, Reddel RR (2001) Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells

These short peptides (typically 2 to 4 amino acids) are designed to interact with specific DNA sequences and modulate gene expression in targeted tissues