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Increased Epididymal levels of glutathione (GSH) (part of the male reproductive tract, where sperm final maturation occurs) can protect the sperm membrane PUFA, playing a protective role in sperm maturation

10.1002/jcb.29457 J

Although most of the early experiments using cuprizone were conducted in mice, a number of studies demonstrated detrimental effects of cuprizone administration to the brain similar to those in mice of other rodents, such as rats [31,32,33,34,35], guinea pigs [31] or hamsters [36, 37]