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Description
As a selective substrate site-targeting inhibitor of nicotinamide N-methyltransferase (NNMT) the cytosolic enzyme responsible for the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor 5-Amino-1MQ is studied as a tool compound for investigating NNMT enzyme activity, NAD salvage pathway interactions, and methylation pathway dynamics in controlled in-vitro experimental systems

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In addition, it increases the activity of certain nerve cells in the central nervous system

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Avoids Serious Complications In patients with severe anaemia, intensive treatment with B12 may result in a sudden drop in potassium (hypokalaemia), which can cause muscle weakness or an irregular heartbeat