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Acute gallbladder disease events, such as cholecystitis or cholelithiasis, have been reported in clinical studies with semaglutide

Inflammopharmacology 14:214221 Sikiric P, Seiwerth S, Brcic L et al (2010) Revised Roberts cytoprotection and adaptive cytoprotection and stable gastric pentadecapeptide BPC 157

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Over the full week between doses, total exposure is comparable