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Most studies demonstrated reductions in oxidative stress markers following curcumin-piperine treatment, including decreases in reactive oxygen species, malondialdehyde, nitrite levels, and protein carbonyl formation, alongside increases in endogenous antioxidant defenses such as glutathione, superoxide dismutase, catalase, and glutathione peroxidase

Collectively, these findings highlight the important role of peptides in modulating gut microbiota and maintaining intestinal immune homeostasis

Assay of protein-bound lipoic acid in tissues by a new enzymatic method

Lancet 353 , 717719 (1999)
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