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Most studies demonstrated reductions in oxidative stress markers following curcumin-piperine treatment, including decreases in reactive oxygen species, malondialdehyde, nitrite levels, and protein carbonyl formation, alongside increases in endogenous antioxidant defenses such as glutathione, superoxide dismutase, catalase, and glutathione peroxidase

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Collectively, these findings highlight the important role of peptides in modulating gut microbiota and maintaining intestinal immune homeostasis

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Assay of protein-bound lipoic acid in tissues by a new enzymatic method

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Lancet 353 , 717719 (1999)

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